Passive transfer of protection against Bacillus anthracis infection in a murine model

被引：76

作者：

Beedham, RJ ^{[1
]}

Turnbull, PCB

Williamson, ED

机构：

[1] DERA Porton Down, CBD, Pathobiol, Salisbury SP4 0JQ, Wilts, England

[2] CAMR Porton Down, Microbiol Anal, Salisbury SP4 0JQ, Wilts, England

[3] DERA Porton Down, CBD, Microbiol, Salisbury SP4 0JQ, Wilts, England

来源：

VACCINE | 2001年 / 19卷 / 31期

关键词：

Bacillus anthracis; correlates of protection; murine model;

D O I：

10.1016/S0264-410X(01)00197-9

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Passive transfer of lymphocytes and sera from mice immunised using two different formulations containing recombinant protective antigen (rPA) have been used to further elucidate the mechanism of protection against Bacillus anthracis infection. The results demonstrated that an antibody response maybe important in protection against B. anthracis infection, under the conditions tested. The results provide further data for the development of an improved anthrax vaccine. Crown Copyright (C) 2001 Published by Elsevier Science Ltd. All rights reserved.

引用

页码：4409 / 4416

页数：8

共 42 条

[1]

Advisory Committee on Dangerous Pathogens, 1995, CAT BIOL AG ACC HAZ

[2]

BEEDHAM RJ, 2000, THESIS OPEN U

[3]

BELTON FC, 1954, BRIT J EXP PATHOL, V35, P144

[4]

CHRISTIE AB, 1987, INFECT DIS EPIDEMIOL, P983

[5] BACILLUS-ANTHRACIS PROTECTIVE ANTIGEN, EXPRESSED IN SALMONELLA-TYPHIMURIUM SL-3261, AFFORDS PROTECTION AGAINST ANTHRAX SPORE CHALLENGE [J].

COULSON, NM ;

FULOP, M ;

TITBALL, RW .

VACCINE, 1994, 12 (15) :1395-1401

[6]

DARLOW HM, 1956, LANCET, V11, P476

[7]

EBEDES H, 1981, P 4 INT C WILDL DIS, P85

[8]

GUIDIRONTANI C, 1993, MOL MICROBIOL, V31, P9

[9]

Hanna P, 1998, CURR TOP MICROBIOL, V225, P13

[10] ON THE ROLE OF MACROPHAGES IN ANTHRAX [J].

HANNA, PC ;

ACOSTA, D ;

COLLIER, RJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (21) :10198-10201

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