Obesity wars: Molecular progress confronts an expanding epidemic

被引：877

作者：

Flier, JS ^{[1
]}

机构：

[1] Beth Israel Deaconess Med Ctr, Dept Med, Div Endocrinol, Boston, MA 02215 USA

来源：

CELL | 2004年 / 116卷 / 02期

关键词：

D O I：

10.1016/S0092-8674(03)01081-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The worldwide prevalence of obesity is increasing at an alarming rate, with major adverse consequences for human health. This "obesity epidemic" is paralleled by a rapid and substantive increase in our understanding of molecular pathways and physiologic systems underlying the regulation of energy balance. While efforts to address the environmental factors that are responsible for the recent "epidemic" must continue, new molecular and physiologic insights into this system offer exciting possibilities for future development of successful therapies.

引用

页码：337 / 350

页数：14

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