ProtTest: selection of best-fit models of protein evolution

被引:2582
作者
Abascal, F [1 ]
Zardoya, R
Posada, D
机构
[1] Univ Vigo, Dept Biochem Genet & Immunol, Vigo 36310, Spain
[2] CSIC, Museo Nacl Ciencias Nat, Dept Biodivers & Evolutionary Biol, E-28006 Madrid, Spain
关键词
D O I
10.1093/bioinformatics/bti263
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Using an appropriate model of amino acid replacement is very important for the study of protein evolution and phylogenetic inference. We have built a tool for the selection of the best-fit model of evolution, among a set of candidate models, for a given protein sequence alignment.
引用
收藏
页码:2104 / 2105
页数:2
相关论文
共 18 条
[1]  
Adachi J, 1996, J MOL EVOL, V42, P459
[2]  
Akaike H, 1973, 2 INT S INFORM THEOR, P199, DOI 10.1007/978-1-4612-1694-0
[3]  
[Anonymous], 1978, Atlas of protein sequence and structure
[4]  
Balding D., 2003, HDB STAT GENETICS, P209
[5]  
Burnham K. P., 2002, MODEL SELECTION MULT
[6]  
CAO Y, 1994, J MOL EVOL, V39, P519
[7]   PAL: an object-oriented programming library for molecular evolution and phylogenetics [J].
Drummond, A ;
Strimmer, K .
BIOINFORMATICS, 2001, 17 (07) :662-663
[8]   BIONJ: An improved version of the NJ algorithm based on a simple model of sequence data [J].
Gascuel, O .
MOLECULAR BIOLOGY AND EVOLUTION, 1997, 14 (07) :685-695
[9]   A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood [J].
Guindon, S ;
Gascuel, O .
SYSTEMATIC BIOLOGY, 2003, 52 (05) :696-704
[10]   THE RAPID GENERATION OF MUTATION DATA MATRICES FROM PROTEIN SEQUENCES [J].
JONES, DT ;
TAYLOR, WR ;
THORNTON, JM .
COMPUTER APPLICATIONS IN THE BIOSCIENCES, 1992, 8 (03) :275-282