Immunology - Licence to kill

被引：289

作者：

Lanzavecchia, A ^{[1
]}

机构：

[1] Basel Inst Immunol, CH-4005 Basel, Switzerland

来源：

NATURE | 1998年 / 393卷 / 6684期

关键词：

D O I：

10.1038/30845

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

To kill invading pathogens, the immune system often has to kill its own infected cells. But how does it control this potentially dangerous mechanism? Three groups have done experiments that support one model of T-cell activation. T-helper cells recognize a specific antigen on professional antigen-presenting cells (APCs), and deliver a signal that activates, or 'licenses', the APC. This activated APC can then stimulate the T-killer cells to mount a response against that antigen.

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收藏

页码：413 / 414

页数：2

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