Yos9p: A sweet-toothed bouncer of the secretory pathway

被引:10
作者
Cormier, JH [1 ]
Pearse, BR [1 ]
Hebert, DN [1 ]
机构
[1] Univ Massachusetts, Dept Biochem & Mol Biol, Program Mol & Cellular Biol, Amherst, MA 01003 USA
关键词
D O I
10.1016/j.molcel.2005.08.029
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In this issue of Molecular Cell, Bhamidipati et al. (2005), Kim et al. (2005), and Szathmary et al. (2005) demonstrate that Yos9p selectively binds to aberrant glycoproteins in the endoplasmic reticulum (ER) and targets them for destruction through the ER-associated protein degradation pathway.
引用
收藏
页码:717 / 719
页数:3
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