Brain natriuretic peptide in the management of heart failure - The versatile neurohormone

被引：62

作者：

de Denus, S

Williamson, DR

机构：

[1] Univ Montreal, Hop Sacre Coeur, Fac Pharm, Montreal, PQ H4J 1C5, Canada

[2] Univ Sci Philadelphia, Coll Pharm, Philadelphia, PA USA

来源：

CHEST | 2004年 / 125卷 / 02期

关键词：

brain natriuretic peptide; congestive heart failure; nesiritide;

D O I：

10.1378/chest.125.2.652

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Brain natriuretic peptide (BNP), also called B-type natriuretic peptide, is a member of a family of structurally related hormones, the natriuretic peptides. Current data suggest that measurement of BNP plasma concentrations is a useful tool in the diagnosis of acute heart failure in patients presenting to an emergency department with acute dyspnea. Furthermore, BNP constitutes a promising new marker of prognosis after an acute coronary syndrome episode and in patients with chronic heart failure. Nesiritide, the human recombinant form of BNP, is a new vasodilator used in the treatment of acute heart failure that has several potential advantages over current drug therapy.

引用

收藏

页码：652 / 668

页数：17

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