The glial identity of neural stem cells

被引:555
作者
Doetsch, F [1 ]
机构
[1] Harvard Univ, Dept Mol & Cellular Biol, Cambridge, MA 02138 USA
关键词
D O I
10.1038/nn1144
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Glia are the most numerous cells in the brain, and their many diverse functions highlight their essential role in the nervous system. Recent studies have revealed an unexpected new role for glia in a wide variety of species, that of stem cells/progenitors in the adult and embryonic brain. Differentiation along the glial lineage may be a default state of development reflected in the progression of stem cells along the neuroepithelial radial glia astrocyte lineage.
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收藏
页码:1127 / 1134
页数:8
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