Secondary prevention in the acute and early chronic phase after ischaemic stroke and transient ischaemic attacks with antiplatelet drugs - is antiplatelet monotherapy still reasonable?

被引：3

作者：

Diener, H. C. ^{[1
,2
]}

Weber, R. ^{[1
,2
]}

Weimar, C. ^{[1
,2
]}

Roether, J. ^{[3
]}

机构：

[1] Univ Duisburg Essen, Dept Neurol, D-45122 Essen, Germany

[2] Univ Duisburg Essen, Stroke Ctr, D-45122 Essen, Germany

[3] Asklepios Klin Altona, Dept Neurol, Hamburg, Germany

来源：

INTERNATIONAL JOURNAL OF CLINICAL PRACTICE | 2011年 / 65卷 / 05期

关键词：

CONTROLLED-TRIAL; HIGH-RISK; CLOPIDOGREL; ASPIRIN; DIPYRIDAMOLE; TIA;

D O I：

10.1111/j.1742-1241.2010.02621.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Intravenous thrombolysis with recombinant tissue plasminogen activator is the only proven medical treatment for acute ischaemic stroke in a time period up to 4.5 h after onset of stroke symptoms. However, only a minority of patients is eligible for intravenous thrombolysis because of delayed presentation or contraindications to thrombolysis. In the remaining patients, early prevention of recurrent stroke is one of the primary therapeutic targets. Numerous prospective studies have shown that the risk of a subsequent or recurrent ischaemic stroke is highest in the first 48-72 h after the initial cerebrovascular ischaemic event (1).

引用

页码：531 / 535

页数：5

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