High titers of CA-125 may be associated with recurrent ischemic strokes in patients with cancer

被引:73
作者
Jovin, TG
Boosupalli, V
Zivkovic, SA
Wechsler, LR
Gebel, JM
机构
[1] Univ Pittsburgh, Med Ctr, Stroke Inst, VA Pittsburgh Healthcare Syst, Pittsburgh, PA 15213 USA
[2] Univ Pittsburgh, Med Ctr, Dept Neurol, VA Pittsburgh Healthcare Syst, Pittsburgh, PA 15213 USA
[3] Childrens Hosp Pittsburgh, Dept Neurol, Pittsburgh, PA USA
关键词
D O I
10.1212/01.WNL.0000163850.07976.63
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
In addition to etiologies common in the general population, strokes in cancer patients may be caused by hypercoagulable states, hyperviscosity, cardiogenic embolism, and neoplastic vessel infiltration. Intravascular mucins were reported in patients with recurrent thromboembolism. The authors report four patients with metastatic cancer, brain infarcts, and other thromboembolic disease with markedly elevated levels of the tumor marker CA-125 and explore possible associations between this mucinous protein and strokes.
引用
收藏
页码:1944 / 1945
页数:2
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