CD1d-restricted mouse Vα14 and human Vα24 T cells:: lymphocytes of innate immunity

被引：63

作者：

Benlagha, K ^{[1
]}

Bendelac, A ^{[1
]}

机构：

[1] Princeton Univ, Dept Biol Mol, Schultz Lab, Princeton, NJ 08544 USA

来源：

SEMINARS IN IMMUNOLOGY | 2000年 / 12卷 / 06期

基金：

美国国家卫生研究院;

关键词：

innate immunity; B-1B cells; gamma delta T cells; NK cells; NKT cells;

D O I：

10.1006/smim.2000.0276

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Mouse V alpha 14 T cells and their human homalogs, V alpha 24 T cells, are prominent subsets of CD1d-restricted T cells. Here we discuss their striking similarities to B-1 B cells and gamma delta T cells and propose that these immune cells mediate various innate strategies in response to endogenous or exogenous danger signals.

引用

页码：537 / 542

页数：6

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