Synaptogenesis and dendritic growth in the cortex opposite unilateral sensorimotor cortex damage in adult rats: A quantitative electron microscopic examination

被引：171

作者：

Jones, TA ^{[1
]}

Kleim, JA ^{[1
]}

Greenough, WT ^{[1
]}

机构：

[1] UNIV ILLINOIS,BECKMAN INST,PROGRAM NEUROSCI,URBANA,IL 61801

来源：

BRAIN RESEARCH | 1996年 / 733卷 / 01期

关键词：

synaptic plasticity; motor cortex; restoration of function; motor learning; layer V; stereology; forelimb behavior;

D O I：

10.1016/0006-8993(96)00792-5

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Unilateral lesions of the forelimb area of the sensorimotor cortex in adult rats resulted in time-dependent increases in the number of synapses per neuron and the volume and membrane surface area oi dendritic processes per neuron within layer V of the contralateral motor cortex in comparison to sham-operated rats. Based on previous findings of a behavioral relationship with increased dendritic arborization, these changes may be related to lesion-induced compensatory changes in the use of the non-impaired (ipsilateral to the lesion) forelimb.

引用

页码：142 / 148

页数：7

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