学术探索
学术期刊
新闻热点
数据分析
智能评审

Hot and cold spots of recombination in the human genome: The reason we should find them and how this can be achieved

被引：67
作者：
Arnheim, N [1 ]
Calabrese, P [1 ]
Nordborg, M [1 ]
机构：
[1] Univ So Calif, Mol & Computat Biol Program, Los Angeles, CA 90089 USA
来源：
AMERICAN JOURNAL OF HUMAN GENETICS | 2003年 / 73卷 / 01期
关键词：
D O I：
10.1086/376419
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
[No abstract available]
引用
收藏
页码：5 / 16
页数：12
相关论文
共 101 条
[1]   NONRANDOM ASSOCIATION OF POLYMORPHIC RESTRICTION SITES IN THE BETA-GLOBIN GENE-CLUSTER [J].
ANTONARAKIS, SE ;
BOEHM, CD ;
GIARDINA, PJV ;
KAZAZIAN, HH .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1982, 79 (01) :137-141
[2]   Lower-than-expected linkage disequilibrium between tightly linked markers in humans suggests a role for gene conversion [J].
Ardlie, K ;
Liu-Cordero, SN ;
Eberle, MA ;
Daly, M ;
Barrett, J ;
Winchester, E ;
Lander, ES ;
Kruglyak, L .
AMERICAN JOURNAL OF HUMAN GENETICS, 2001, 69 (03) :582-589
[3]   Patterns of linkage disequilibrium in the human genome [J].
Ardlie, KG ;
Kruglyak, L ;
Seielstad, M .
NATURE REVIEWS GENETICS, 2002, 3 (04) :299-309
[4]   Crossover breakpoint mapping identifies a subtelomeric hotspot for male meiotic recombination [J].
Badge, RM ;
Yardley, J ;
Jeffreys, AJ ;
Armour, JAL .
HUMAN MOLECULAR GENETICS, 2000, 9 (08) :1239-1244
[5]  
BOTSTEIN D, 1980, AM J HUM GENET, V32, P314
[6]   Comprehensive human genetic maps: Individual and sex-specific variation in recombination [J].
Broman, KW ;
Murray, JC ;
Sheffield, VC ;
White, RL ;
Weber, JL .
AMERICAN JOURNAL OF HUMAN GENETICS, 1998, 63 (03) :861-869
[7]   Genetic analysis of meiotic recombination in humans by use of sperm typing: Reduced recombination within a heterozygous paracentric inversion of chromosome 9q32-q34.3 [J].
Brown, GM ;
Leversha, M ;
Hulten, M ;
Ferguson-Smith, MA ;
Affara, NA ;
Furlong, RA .
AMERICAN JOURNAL OF HUMAN GENETICS, 1998, 62 (06) :1484-1492
[8]   Meiotic recombination and flanking marker exchange at the highly unstable human minisatellite CEB1 (D2S90) [J].
Buard, J ;
Shone, AC ;
Jeffreys, AJ .
AMERICAN JOURNAL OF HUMAN GENETICS, 2000, 67 (02) :333-344
[9]   INTEGRATED HUMAN GENOME-WIDE MAPS CONSTRUCTED USING THE CEPH REFERENCE PANEL [J].
BUETOW, KH ;
WEBER, JL ;
LUDWIGSEN, S ;
SCHERPBIERHEDDEMA, T ;
DUYK, GM ;
SHEFFIELD, VC ;
WANG, ZY ;
MURRAY, JC .
NATURE GENETICS, 1994, 6 (04) :391-393
[10]   Using haplotype blocks to map human complex trait loci [J].
Cardon, LR ;
Abecasis, GR .
TRENDS IN GENETICS, 2003, 19 (03) :135-140
12345678910