Expression of a novel rat protein tyrosine phosphatase gene

被引：8

作者：

Carter, DA ^{[1
]}

机构：

[1] Univ Wales Coll Cardiff, Sch Mol & Med Biosci, Cardiff CF1 3US, S Glam, Wales

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 1998年 / 1442卷 / 2-3期

基金：

英国医学研究理事会;

关键词：

protein tyrosine phosphatase; pituitary gland; (rat);

D O I：

10.1016/S0167-4781(98)00173-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The cDNA sequence and expression of a novel rat protein tyrosine phosphatase (PTP) gene is reported. The predicted amino acid sequence is similar to rat PRL-1, but is more closely related to human PTP4A, another member of the recently identified fourth group of PTPs. Therefore, multiple PTPs of this group are expressed in mammalian species. The novel rat PTP gene is expressed in the anterior pituitary gland in a sexually dimorphic pattern which is indicative of a specialized role in endocrine function. (C) 1998 Elsevier Science B.V. All rights reserved.

引用

页码：405 / 408

页数：4

共 8 条

[1] LEUKEMIA INHIBITORY FACTOR EXPRESSION IN CULTURED RAT ANTERIOR-PITUITARY IS REGULATED BY GLUCOCORTICOIDS [J].

CARTER, DA .

JOURNAL OF NEUROENDOCRINOLOGY, 1995, 7 (08) :623-628

[2] PRL-1, A UNIQUE NUCLEAR-PROTEIN TYROSINE PHOSPHATASE, AFFECTS CELL-GROWTH [J].

DIAMOND, RH ;

CRESSMAN, DE ;

LAZ, TM ;

ABRAMS, CS ;

TAUB, R .

MOLECULAR AND CELLULAR BIOLOGY, 1994, 14 (06) :3752-3762

[3] QUANTITATION OF CHANGES IN THE EXPRESSION OF MULTIPLE GENES BY SIMULTANEOUS POLYMERASE CHAIN-REACTION [J].

DUKAS, K ;

SARFATI, P ;

VAYSSE, N ;

PRADAYROL, L .

ANALYTICAL BIOCHEMISTRY, 1993, 215 (01) :66-72

[4] Receptor-like protein-tyrosine phosphatase α specifically inhibits insulin-increased prolactin gene expression [J].

Jacob, KK ;

Sap, J ;

Stanley, FM .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (08) :4800-4809

[5] IMPROVED TOOLS FOR BIOLOGICAL SEQUENCE COMPARISON [J].

PEARSON, WR ;

LIPMAN, DJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (08) :2444-2448

[6]

Sambrook J., 2002, MOL CLONING LAB MANU

[7] Protein tyrosine phosphatases in signaling [J].

Streuli, M .

CURRENT OPINION IN CELL BIOLOGY, 1996, 8 (02) :182-188

[8] Characterization and genomic mapping of genes and pseudogenes of a new human protein tyrosine phosphatase [J].

Zhao, ZY ;

Lee, CC ;

Monckton, DG ;

Yazdani, A ;

Coolbaugh, MI ;

Li, XR ;

Bailey, J ;

Shen, Y ;

Caskey, CT .

GENOMICS, 1996, 35 (01) :172-181

← 1 →