First observation of two consecutive γ turns in a crystalline linear dipeptide

被引：61

作者：

Jiménez, AI ^{[1
]}

Ballano, G ^{[1
]}

Cativiela, C ^{[1
]}

机构：

[1] Univ Zaragoza, ICMA, Dept Quim Organ, E-50009 Zaragoza, Spain

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2005年 / 44卷 / 03期

关键词：

beta turn; conformation analysis; hydrogen bonds; peptide folding; structure elucidation;

D O I：

10.1002/anie.200461230

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) Which way to turn? For the very first time, a linear dipeptide has been shown to accommodate two consecutive γ turns in the solid state. An aminocyclopropane carboxylic acid has overridden the tendency of proline to induce a β-turn conformation in Pro-Xaa dipeptides (see X-ray crystal structure; blue: N, red: O, dashed lines show H bonds).

引用

页码：396 / 399

页数：4

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