Specification of neuronal fates in the ventral neural tube

被引：406

作者：

Briscoe, J

Ericson, J

机构：

[1] Natl Inst Med Res, Div Dev Neurobiol, London NW7 1AA, England

[2] Karolinska Inst, Med Nobel Inst, Dept Mol & Cell Biol, S-17177 Stockholm, Sweden

来源：

CURRENT OPINION IN NEUROBIOLOGY | 2001年 / 11卷 / 01期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/S0959-4388(00)00172-0

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The generation of distinct classes of neurons at defined positions is a fundamental step in the development of the vertebrate central nervous system. Recent work has begun to reveal the extracellular signals and transcriptional mediators that direct the pattern of generation of distinct neuronal subtypes in the neural tube. This work has provided a framework to understand the patterning of the ventral neural tube and is permitting molecular analyses of the assembly of functional neuronal circuits.

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收藏

页码：43 / 49

页数：7

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