Thrombolysis in stroke patients aged 80 years and older:: Swiss survey of IV thrombolysis

被引:107
作者
Engelter, ST
Reichhart, M
Sekoranja, L
Georgiadis, D
Baumann, A
Weder, B
Müller, F
Lüthy, R
Arnold, M
Michel, P
Mattle, HP
Tettenborn, B
Hungerbühler, HJ
Baumgartner, RW
Sztajzel, R
Bogousslavsky, J
Lyrer, PA
机构
[1] Univ Basel Hosp, Neurol Clin, Dept Neurol, CH-4031 Basel, Switzerland
[2] Univ Basel Hosp, Dept Neurol, Stroke Unit, CH-4031 Basel, Switzerland
[3] Univ Lausanne Hosp, Lausanne, Switzerland
[4] Univ Hosp Bern, CH-3010 Bern, Switzerland
[5] Univ Hosp Geneva, Geneva, Switzerland
[6] Univ Zurich Hosp, CH-8091 Zurich, Switzerland
[7] Cantonal Hosp Aarau, Aarau, Switzerland
[8] Cantonal Hosp St Gallen, St Gallen, Switzerland
[9] Triemli Hosp Zurich, Dept Internal Med, Zurich, Switzerland
关键词
D O I
10.1212/01.wnl.0000183702.04080.27
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
This databank-based, multicenter study compared all stroke patients with IV tissue plasminogen activator aged >= 80 years (n = 38) and those < 80 years old (n = 287). Three-month mortality was higher in older patients. Favorable outcome (modified Rankin scale <= 1) and intracranial hemorrhage (asymptomatic/symptomatic/fatal) were similarly frequent in both groups. Logistic regression showed that stroke severity, time to thrombolysis, glucose level, and history of coronary heart disease independently predicted outcome, whereas age did not.
引用
收藏
页码:1795 / 1798
页数:4
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