Supporting tool suite for production proteomics

被引:31
作者
Ma, Ze-Qiang [2 ]
Tabb, David L. [1 ,2 ,3 ,4 ]
Burden, Joseph [1 ,3 ]
Chambers, Matthew C. [2 ]
Cox, Matthew B. [1 ,3 ]
Cantrell, Michael J. [1 ]
Ham, Amy-Joan L. [1 ,4 ]
Litton, Michael D. [1 ]
Oreto, Michael R. [1 ]
Schultz, William C. [1 ,3 ]
Sobecki, Scott M. [1 ,3 ]
Tsui, Tina Y. [3 ]
Wernke, Gregory R. [1 ,3 ]
Liebler, Daniel C. [1 ,4 ]
机构
[1] Vanderbilt Univ, Med Ctr, Jim Ayers Inst Precanc Detect & Diag, Vanderbilt Ingram Canc Ctr, Nashville, TN 37232 USA
[2] Vanderbilt Univ, Med Ctr, Dept Biomed Informat, Nashville, TN 37232 USA
[3] Vanderbilt Univ, Med Ctr, Mass Spectrometry Res Ctr, Nashville, TN 37232 USA
[4] Vanderbilt Univ, Med Ctr, Dept Biochem, Nashville, TN 37232 USA
关键词
IDENTIFICATION;
D O I
10.1093/bioinformatics/btr544
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The large amount of data produced by proteomics experiments requires effective bioinformatics tools for the integration of data management and data analysis. Here we introduce a suite of tools developed at Vanderbilt University to support production proteomics. We present the Backup Utility Service tool for automated instrument file backup and the ScanSifter tool for data conversion. We also describe a queuing system to coordinate identification pipelines and the File Collector tool for batch copying analytical results. These tools are individually useful but collectively reinforce each other. They are particularly valuable for proteomics core facilities or research institutions that need to manage multiple mass spectrometers. With minor changes, they could support other types of biomolecular resource facilities.
引用
收藏
页码:3214 / 3215
页数:2
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