Trends in five-year survival and risk of recurrent stroke after first-ever stroke in the Perth community stroke study

被引:76
作者
Hardie, K
Jamrozik, K
Hankey, GJ
Broadhurst, RJ
Anderson, C
机构
[1] Royal Perth Hosp, Dept Neurol, Stroke Unit, Perth, WA 6001, Australia
[2] Univ London Imperial Coll Sci Technol & Med, London, England
[3] Univ Western Australia, Sch Populat Hlth, Perth, WA 6009, Australia
[4] Univ Western Australia, Sch Med & Pharmacol, Perth, WA 6009, Australia
[5] Univ Auckland, Clin Trials Res Unit, Auckland 1, New Zealand
关键词
stroke; morbidity; trends; epidemiology; Australia;
D O I
10.1159/000083253
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Background: Few studies provide information on trends in the long-term outcome of stroke. We aimed to determine trends in survival and recurrent stroke, over 5 years after first-ever stroke, for 2 cohorts of patients enrolled in the Perth Community Stroke Study in 1989 90 and 1995-96. Methods: For 12-month periods beginning February 1989 and February 1995, all individuals with an acute stroke who were resident in a geographically-defined and representative region of Perth, Western Australia, were registered and followed-up prospectively 5 years after the index event. Results: The 5-year cumulative risk of death was 59% (95% confidence interval (CI) 53%, 65%) and 58% (95% CI 52%, 65%) for the 1989-90 and 1995-96 cohorts, respectively (p = 0.94). The 5-year cumulative risk of first recurrent stroke was 32% (95% CI 25%, 40%) and 23% (95% CI 16%, 30%) for the 1989-90 and 1995-96 cohorts, respectively (p = 0.07). Conclusions: Although no statistically significant improvement occurred in 5-year survival after first-ever stroke in Perth between 1989-90 and 1995-96, there was a statistically nonsignificant trend towards a smaller cumulative risk of recurrent stroke over 5 years after a first-ever stroke. Serial community-based studies of the incidence and outcome of stroke are an important means of monitoring the translation of proven preventive interventions to improvements in population health. Copyright (C) 2005 S. Karger AG, Basel.
引用
收藏
页码:179 / 185
页数:7
相关论文
共 32 条
[1]   COLLABORATIVE OVERVIEW OF RANDOMIZED TRIALS OF ANTIPLATELET THERAPY .1. PREVENTION OF DEATH, MYOCARDIAL-INFARCTION, AND STROKE BY PROLONGED ANTIPLATELET THERAPY IN VARIOUS CATEGORIES OF PATIENTS [J].
ALTMAN, R ;
CARRERAS, L ;
DIAZ, R ;
FIGUEROA, E ;
PAOLASSO, E ;
PARODI, JC ;
CADE, JF ;
DONNAN, G ;
EADIE, MJ ;
GAVAGHAN, TP ;
OSULLIVAN, EF ;
PARKIN, D ;
RENNY, JTG ;
SILAGY, C ;
VINAZZER, H ;
ZEKERT, F ;
ADRIAENSEN, H ;
BERTRANDHARDY, JM ;
BRAN, M ;
DAVID, JL ;
DRICOT, J ;
LAVENNEPARDONGE, E ;
LIMET, R ;
LOWENTHAL, A ;
MORIAU, M ;
SCHAPIRA, S ;
SMETS, P ;
SYMOENS, J ;
VERHAEGHE, R ;
VERSTRAETE, M ;
ATALLAH, A ;
BARNETT, H ;
BATISTA, R ;
BLAKELY, J ;
CAIRNS, JA ;
COTE, R ;
CROUCH, J ;
EVANS, G ;
FINDLAY, JM ;
GENT, M ;
LANGLOIS, Y ;
LECLERC, J ;
NORRIS, J ;
PINEO, GF ;
POWERS, PJ ;
ROBERTS, R ;
SCHWARTZ, L ;
SICURELLA, J ;
TAYLOR, W ;
THEROUX, P .
BMJ-BRITISH MEDICAL JOURNAL, 1994, 308 (6921) :81-100
[2]   PREDICTING SURVIVAL FOR 1 YEAR AMONG DIFFERENT SUBTYPES OF STROKE - RESULTS FROM THE PERTH-COMMUNITY-STROKE STUDY [J].
ANDERSON, CS ;
JAMROZIK, KD ;
BROADHURST, RJ ;
STEWARTWYNNE, EG .
STROKE, 1994, 25 (10) :1935-1944
[3]   ASCERTAINING THE TRUE INCIDENCE OF STROKE - EXPERIENCE FROM THE PERTH COMMUNITY STROKE STUDY, 1989-1990 [J].
ANDERSON, CS ;
JAMROZIK, KD ;
BURVILL, PW ;
CHAKERA, TMH ;
JOHNSON, GA ;
STEWARTWYNNE, EG .
MEDICAL JOURNAL OF AUSTRALIA, 1993, 158 (02) :80-84
[4]  
*AUSTR BUR STAT, 1998, DEATHS AUSTR
[5]   Benefit of carotid endarterectomy in patients with symptomatic moderate or severe stenosis [J].
Barnett, HJM ;
Taylor, W ;
Eliasziw, M ;
Fox, AJ ;
Ferguson, GG ;
Haynes, RB ;
Rankin, RN ;
Clagett, GP ;
Hachinski, VC ;
Sackett, DL ;
Thorpe, KE ;
Meldrum, HE ;
Spence, JD .
NEW ENGLAND JOURNAL OF MEDICINE, 1998, 339 (20) :1415-1425
[6]   INTERNATIONAL TRENDS IN STROKE MORTALITY - 1970-1985 [J].
BONITA, R ;
STEWART, A ;
BEAGLEHOLE, R .
STROKE, 1990, 21 (07) :989-992
[7]   CHANGES IN STROKE INCIDENCE AND CASE-FATALITY IN AUCKLAND, NEW-ZEALAND, 1981-91 [J].
BONITA, R ;
BROAD, JB ;
BEAGLEHOLE, R .
LANCET, 1993, 342 (8885) :1470-1473
[8]  
Brown RD, 1996, STROKE, V27, P373
[9]   Effect of HMGcoA reductase inhibitors on stroke - A meta-analysis of randomized, controlled trials [J].
Bucher, HC ;
Griffith, LE ;
Guyatt, GH .
ANNALS OF INTERNAL MEDICINE, 1998, 128 (02) :89-+
[10]   LONG-TERM RISK OF RECURRENT STROKE AFTER A FIRST-EVER STROKE - THE OXFORDSHIRE COMMUNITY STROKE PROJECT [J].
BURN, J ;
DENNIS, M ;
BAMFORD, J ;
SANDERCOCK, P ;
WADE, D ;
WARLOW, C .
STROKE, 1994, 25 (02) :333-337