Circadian elevation of IL-6 levels in Muckle-Wells syndrome: a disorder of the neuro-immune axis?

被引：22

作者：

Gerbig, AW

Dahinden, CA

Mullis, P

Hunziker, T ^{[1
]}

机构：

[1] Univ Bern, Dept Dermatol, CH-3010 Bern, Switzerland

[2] Univ Bern, Dept Immunol, CH-3010 Bern, Switzerland

[3] Univ Bern, Childrens Hosp, CH-3010 Bern, Switzerland

来源：

QJM-AN INTERNATIONAL JOURNAL OF MEDICINE | 1998年 / 91卷 / 07期

关键词：

D O I：

10.1093/qjmed/91.7.489

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Muckle-Wells syndrome (MWS) is a rare autosomal dominant hereditary disorder characterized by chronic recurrent urticaria, arthralgia, sensorineural deafness, and in some cases nephropathy due to amyloidosis (AA type). We report a 21-year-old woman and her father, both suffering from this syndrome, in whom elevated serum levels of IL-6 could be documented during the flares of urticaria, and discuss the relevance of this finding for MWS.

引用

页码：489 / 492

页数：4

共 11 条

[1] C-KIT LIGAND - A UNIQUE POTENTIATOR OF MEDIATOR RELEASE BY HUMAN LUNG MAST-CELLS [J].