Features and trends in Helicobacter pylori antibiotic resistance in Lisbon area, Portugal (1990-1999)

被引：110

作者：

Cabrita, J

Oleastro, M

Matos, R

Manhente, A

Cabral, J

Barros, R

Lopes, AI

Ramalho, P

Neves, BC

Guerreiro, AS

机构：

[1] Inst Nacl Saude, Bacteriol Lab, P-1649016 Lisbon, Portugal

[2] Hosp D Estefania, Fac Farm Lisboa, Lisbon, Portugal

[3] Hosp D Estefania, Unidade Gastrenterol, Serv Patol Clin, Lisbon, Portugal

[4] Hosp Santa Maria, Unidade Gastrenterol Pediat, Lisbon, Portugal

[5] Hosp Pulido Valente, Clin Univ Med Interna & Gastrenterol, Lisbon, Portugal

来源：

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 2000年 / 46卷 / 06期

关键词：

D O I：

10.1093/jac/46.6.1029

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The features of Helicobacter pylori antibiotic resistance in Lisbon from 1990 to 1999 were studied. Overall resistance rates to amoxycillin, tetracycline, metronidazole, clarithromycin and ciprofloxacin were 0, 0, 30.6, 19.0 and 9.6%, respectively. The incidence of resistance to clarithromycin was much higher in isolates from children (44.8%) than adults (14.6%). For metronidazole, the contrary was observed (children: 19.0%, adults: 32.3%). Ciprofloxacin-resistant isolates were all from adult patients. Concerning the adult population, the resistance rate to metronidazole showed a slight increase during the decade, while for clarithromycin and ciprofloxacin a significant increase was observed (4.6 to 22.0% and 0 to 20.9%, respectively).

引用

页码：1029 / 1031

页数：3

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