c-Fos expression in rat brain after repetitive transcranial magnetic stimulation

被引：38

作者：

Doi, W ^{[1
]}

Sato, D ^{[1
]}

Fukuzako, H ^{[1
]}

Takigawa, M ^{[1
]}

机构：

[1] Kagoshima Univ, Fac Med, Dept Neuropsychiat, Kagoshima 8908520, Japan

来源：

NEUROREPORT | 2001年 / 12卷 / 06期

关键词：

c-Fos immunohistochemistry; electroconvulsive shock; transcranial magnetic stimulation;

D O I：

10.1097/00001756-200105080-00050

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We investigated neuronal response to repetitive transcranial magnetic stimulation (rTMS) and electroconvulsive shock (ECS) in terms of c-Fos expression. In rats at postnatal day 49, six rTMS sessions induced widespread nuclear c-Fos-like immunoreactivity in frontal cortex lateral orbital cortex, striatum, lateral septal nucleus, piriform cortex, dentate gyrus, Ammon's horn, cingulate cortex, parietal cortex, thalamus, occipital cortex, and amygdala; this reactivity was greater than with two sessions of rTMS or sham rTMS. ECS produced even stronger c-Fos expression than six sessions of rTMS in all regions except thalamus (no difference) and striatum (stronger with rTMS). Thus, functional modification of neuroanatomic substrates as demonstrated by c-Fos expression may partially differ between rTMS and ECS. NeuroReport 12:1307-1310 (C) 2001 Lippincott Williams & Wilkins.

引用

页码：1307 / 1310

页数：4

共 18 条

[1]

[Anonymous], RAT BRAIN STEREOTAXI

[2]

[Anonymous], TRANSCRANIAL MAGNETI

[3]

BARKER AT, 1985, LANCET, V1, P1106

[4] MOUSE-BRAIN C-FOS MESSENGER-RNA DISTRIBUTION FOLLOWING A SINGLE ELECTROCONVULSIVE SHOCK [J].

DAVAL, JL ;

NAKAJIMA, T ;

GLEITER, CH ;

POST, RM ;

MARANGOS, PJ .

JOURNAL OF NEUROCHEMISTRY, 1989, 52 (06) :1954-1957

[5]

Greenberg BD, 1997, AM J PSYCHIAT, V154, P867

[6] Effect of transcranial magnetic stimulation in posttraumatic stress disorder: A preliminary study [J].

Grisaru, N ;

Amir, M ;

Cohen, H ;

Kaplan, Z .

BIOLOGICAL PSYCHIATRY, 1998, 44 (01) :52-55

[7] Repetitive transcranial magnetic stimulation is as effective as electroconvulsive therapy in the treatment of nondelusional major depressive disorder: An open study [J].

Grunhaus, L ;

Dannon, PN ;

Schreiber, S ;

Dolberg, OH ;

Amiaz, R ;

Ziv, R ;

Lefkifter, E .

BIOLOGICAL PSYCHIATRY, 2000, 47 (04) :314-324

[8] Transcranial magnetic stimulation and auditory hallucinations in schizophrenia [J].

Hoffman, RE ;

Boutros, NN ;

Hu, S ;

Berman, RM ;

Krystal, JH ;

Charney, DS .

LANCET, 2000, 355 (9209) :1073-1075

[9] APPLICATION OF TRANSCRANIAL MAGNETIC STIMULATION IN TREATMENT OF DRUG-RESISTANT MAJOR DEPRESSION - A REPORT OF 2 CASES [J].

HOFLICH, G ;

KASPER, S ;

HUFNAGEL, A ;

RUHRMANN, S ;

MOLLER, HJ .

HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL, 1993, 8 (05) :361-365

[10] TRANSCRANIAL MAGNETIC STIMULATION (TMS) IN THE TREATMENT OF MAJOR DEPRESSION - A PILOT-STUDY [J].

KOLBINGER, HM ;

HOFLICH, G ;

HUFNAGEL, A ;

MOLLER, HJ ;

KASPER, S .

HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL, 1995, 10 (04) :305-310

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