Elements of immunity - The instructive role of innate immunity in the acquired immune response

被引：1327

作者：

Fearon, DT ^{[1
]}

Locksley, RM ^{[1
]}

机构：

[1] UNIV CALIF SAN FRANCISCO, DEPT MED, SAN FRANCISCO, CA 94143 USA

来源：

SCIENCE | 1996年 / 272卷 / 5258期

基金：

英国惠康基金;

关键词：

D O I：

10.1126/science.272.5258.50

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Innate immunity has been considered only to provide rapid, incomplete antimicrobial host defense until the slower, more definitive acquired immune response develops. However, innate immunity may have an additional role in determining which antigens the acquired immune system responds to and the nature of that response. Knowledge of the molecules and pathways involved may create new therapeutic options for infectious and autoimmune diseases.

引用

页码：50 / 54

页数：5

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