Chemical synthesis of polylactide and its copolymers for medical applications

被引：149

作者：

Bendix, D ^{[1
]}

机构：

[1] Boehringer Ingelheim KG, GE Spezial Prod, D-55216 Ingelheim, Germany

来源：

POLYMER DEGRADATION AND STABILITY | 1998年 / 59卷 / 1-3期

关键词：

D O I：

10.1016/S0141-3910(97)00149-3

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Polylactide and its copolymers are produced by ring-opening polymerization of cyclic monomers. The monomers are synthesized by thermal induced unzipping reactions of oligomers. A large variety of processes can be used to polymerize these monomers. The use as starting materials in the medical industry requires a high purity of all compounds and advanced quality systems. Regulatory aspects such as cGMP and Drug or Device Master Files have to be taken into account when producing polylactides for medical applications. (C) 1998 Elsevier Science Limited. All rights reserved.

引用

页码：129 / 135

页数：7