Emerging role of myeloperoxidase and oxidant stress markers in cardiovascular risk assessment

被引:128
作者
Brennan, ML
Hazen, SL
机构
[1] Cleveland Clin Fdn, Ctr Cardiovasc Diagnost & Prevent, Cleveland, OH 44195 USA
[2] Cleveland Clin Fdn, Dept Cell Biol, Cleveland, OH 44195 USA
[3] Cleveland Clin Fdn, Dept Cardiovasc Med, Cleveland, OH 44195 USA
关键词
myeloperoxidase; cardiovascular disease; inflammation; oxidation; nitric oxide;
D O I
10.1097/00041433-200308000-00003
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The inflammatory protein myeloperoxidase is present, active and mechanistically poised to participate in the initiation and progression of cardiovascular disease. The many links between myeloperoxidase, oxidation and cardiovascular disease suggest this leukocyte protein may have clinical utility in risk stratification for cardiovascular disease status and outcomes.
引用
收藏
页码:353 / 359
页数:7
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