Prognostic value of copeptin in patients with acute stroke

被引：23

作者：

Jiao, Lidong ^{[1
]}

Chu, Changbiao ^{[1
]}

Zhou, Shijie ^{[2
]}

机构：

[1] Capital Med Univ, Xuanwu Hosp, Dept Neurol, Beijing 100053, Peoples R China

[2] Sichuan Sci & Cellular Biotechnol Res Inst, Dept Med, Chengdu 610041, Peoples R China

来源：

EXPERT REVIEW OF NEUROTHERAPEUTICS | 2015年 / 15卷 / 05期

关键词：

acute stroke; copeptin; prognosis; systematic review; ACUTE ISCHEMIC-STROKE; ACUTE INTRACEREBRAL HEMORRHAGE; ACUTE MYOCARDIAL-INFARCTION; TRAUMATIC BRAIN-INJURY; PLASMA COPEPTIN; RISK STRATIFICATION; STABLE PEPTIDE; MARKER; BIOMARKERS; BLOOD;

D O I：

10.1586/14737175.2015.1030734

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Context: There is a need to improve stroke care through the prompt identification of stroke patients at increased risk of an adverse outcome. Objective: To evaluate the prognostic value of copeptin in patients with stroke. Methods: We systematically searched PubMed and Embase for relevant studies. Poor outcome and mortality were analyzed. Results: Twelve studies, containing 2682 patients, were included. Pooled analysis showed that copeptin is an independent prognostic marker of poor outcome after acute stroke and there is a borderline effect of copeptin in predicting mortality after acute stroke. Conclusions: Copeptin is an independent predictor of poor outcome and mortality for patients with acute stroke.

引用

页码：563 / 570

页数：8

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