Current status of cellular therapy for ischemic heart disease

被引：27

作者：

Fazel, S ^{[1
]}

Tang, GHL ^{[1
]}

Angoulvant, D ^{[1
]}

Cimini, M ^{[1
]}

Weisel, RD ^{[1
]}

Li, RK ^{[1
]}

Yau, TM ^{[1
]}

机构：

[1] Univ Toronto, Toronto Gen Hosp,Richard Lewar Ctr Excellence, Div Cardiovasc Surg,Heart & Stroke Fdn, Univ Hlth Network,Dept Surg, Toronto, ON M5G 2C4, Canada

来源：

ANNALS OF THORACIC SURGERY | 2005年 / 79卷 / 06期

关键词：

D O I：

10.1016/j.athoracsur.2005.02.085

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Cellular therapy for acute myocardial infarction and ischemic cardiomyopathy has entered clinical trials across the globe. Early promising results have now provided the justification for larger randomized and blinded trials to address the efficacy of cellular therapy. A variety of fresh or cultured autologous cells have been delivered by catheter-guided endocardial, catheter-guided intracoronary, catheter-guided transvenous, and direct epicardial routes. This review will summarize the clinical data and highlight salient basic science data that support the ongoing efforts to identify the optimal cellular therapy both for acute myocardial infarction and chronic ischemic cardiomyopathy patients. (c) 2005 by The Society of Thoracic Surgeons.

引用

页码：S2238 / S2247

页数：10

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