A prospective survey of patients with valvular heart disease in Europe:: The Euro Heart Survey on Valvular Heart Disease

被引:2505
作者
Iung, B [1 ]
Baron, G [1 ]
Butchart, EG [1 ]
Delahaye, F [1 ]
Gohlke-Bärwolf, C [1 ]
Levang, OW [1 ]
Tornos, P [1 ]
Vanoverschelde, JL [1 ]
Vermeer, F [1 ]
Boersma, E [1 ]
Ravaud, P [1 ]
Vahanian, A [1 ]
机构
[1] Hop Xavier Bichat, Dept Cardiol, F-75018 Paris, France
关键词
valvular heart disease; echocardiography; cardiac surgery;
D O I
10.1016/S0195-668X(03)00201-X
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Aims To identify the characteristics, treatment, and outcomes of contemporary patients with valvular heart disease (VHD) in Europe, and to examine adherence to guidelines. Methods and results The Euro Heart Survey on VHD was conducted from April to July 2001 in 92 centres from 25 countries; it included prospectively 5001 adults with moderate to severe native VHD, infective endocarditis, or previous valve intervention. VHD was native in 71.9% of patients and 28.1% had had a previous intervention. Mean age was 64+/-14 years. Degenerative aetiologies were the most frequent in aortic VHD and mitral regurgitation while most cases of mitral stenosis were of rheumatic origin. Coronary angiography was used in 85.2% of patients before intervention. Of the 1269 patients who underwent intervention, prosthetic replacement was performed in 99.0% of aortic VHD, percutaneous dilatation in 33.9% of mitral. stenosis, and valve repair in 46.5% of mitral regurgitation; 31.7% of patients had 2:1 associated procedure. Of patients with severe, symptomatic, single VHD, 31.8% did not undergo intervention, most frequently because of comorbidities. In asymptomatic patients, accordance with guidelines ranged between 66.0 and 78.5%. Operative mortality was <5% for single VHD. Conclusions This survey provides unique contemporary data on characteristics and management of patients with VHD. Adherence to guidelines is globally satisfying as regards investigations and interventions. (C) 2003 The European Society of Cardiology. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:1231 / 1243
页数:13
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