Retinoids run rampant: Multiple roles during spinal cord and motor neuron development

被引：51

作者：

Appel, B ^{[1
]}

Eisen, JS

机构：

[1] Vanderbilt Univ, Dept Biol Sci, Nashville, TN 37235 USA

[2] Univ Oregon, Inst Neurosci, Eugene, OR 97403 USA

来源：

NEURON | 2003年 / 40卷 / 03期

关键词：

TRANSCRIPTIONAL CODES; PRIMARY NEUROGENESIS; CHICK-EMBRYO; ACID; IDENTITY; DIFFERENTIATION; FGF; SPECIFICATION; SIGNALS;

D O I：

10.1016/S0896-6273(03)00688-3

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Learning how the incredible diversity of neurons in the vertebrate central nervous system (CNS) is generated is a central focus of developmental neuroscience. Three studies in the September 25, 2003, issue of Neuron bring us closer to this goal by revealing how the interplay between Fibroblast Growth Factor (FGF), retinoic acid (RA), and Sonic hedgehog (Shh) signaling regulate progression of spinal cord progenitor cells through various phases of development and specify particular types of spinal motor neurons (MNs).

引用

页码：461 / 464

页数：4

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