Nature and nurture - Lessons from chemical carcinogenesis

被引：281

作者：

Luch, A ^{[1
]}

机构：

[1] MIT, Ctr Canc Res, Cambridge, MA 02139 USA

来源：

NATURE REVIEWS CANCER | 2005年 / 5卷 / 02期

关键词：

D O I：

10.1038/nrc1546

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The roles of genetic constitution versus environmental factors in cancer development have been a matter of debate even long before the discovery of 'oncogenes'. Evidence from epidemiological, occupational and migration studies has consistently pointed to environmental factors as the major contributing factors to cancer, so it seems reasonable to discuss the importance of chemical carcinogenesis in the present 'age of cancer genetics'.

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页码：113 / 125

页数：13

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