Membrane protein structure: Prediction versus reality

被引：178

作者：

Elofsson, Arne ^{[1
]}

von Heijne, Gunnar ^{[1
]}

机构：

[1] Stockholm Univ, Dept Biochem & Biophys, Cte Biomembrane Res, Stockholm Bioinformat Ctr, SE-10691 Stockholm, Sweden

来源：

ANNUAL REVIEW OF BIOCHEMISTRY | 2007年 / 76卷

关键词：

bioinformatics; membrane protein structure prediction; topology;

D O I：

10.1146/annurev.biochem.76.052705.163539

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Since high-resolution structural data are still scarce, different kinds of theoretical structure prediction algorithms are of major importance in membrane protein biochemistry. But how well do the current prediction methods perform? Which structural features can be predicted and which cannot? And what can we expect in the next few years?.

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收藏

页码：125 / 140

页数：16

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