Homocysteine plasma levels in patients with migraine with aura

被引：51

作者：

Moschiano, Franca ^{[1
,2
]}

D'Amico, Domenico ^{[4
]}

Usai, Susanna ^{[4
]}

Grazzi, Licia ^{[4
]}

Di Stefano, Maria ^{[2
]}

Ciusani, Emilio ^{[4
]}

Erba, Nicoletta ^{[3
]}

Bussone, Gennaro ^{[4
]}

机构：

[1] L Mandic Hosp, Merate, LC, Italy

[2] AO Osped Lecco, Merate Hosp, Headache Ctr, Lecce, Italy

[3] AO Osped Lecco, Merate Hosp, Dept Lab Med, Lecce, Italy

[4] Neurol Inst C Besta IRCCS, Headache Ctr, Milan, Italy

来源：

NEUROLOGICAL SCIENCES | 2008年 / 29卷 / Suppl 1期

关键词：

migraine with aura (MA); homocysteine; hyperhomocysteinaemia; stroke;

D O I：

10.1007/s10072-008-0917-2

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We investigated homocysteine plasma levels in 136 MA sufferers and in 117 sex- and age-matched controls. Mean homocysteine plasma levels - as well as the proportion of subjects with hyperhomocysteinaemia were significantly higher in patients with MA than in healthy controls. Hyperhomocysteinaemia may be a link between MA and ischaemic stroke.

引用

页码：S173 / S175

页数：3

共 25 条

[1] Total plasma homocysteine level and risk of cardiovascular disease -: A meta-analysis of prospective cohort studies [J].

Bautista, LE ;

Arenas, IA ;

Peñuela, A ;

Martínez, LX .

JOURNAL OF CLINICAL EPIDEMIOLOGY, 2002, 55 (09) :882-887

[2] Homocysteine lowering and cardiovascular events after acute myocardial infarction [J].

Bonaa, KH ;

Njolstad, I ;

Ueland, PM ;

Schirmer, H ;

Tverdal, A ;

Steigen, T ;

Wang, H ;

Nordrehaug, JE ;

Arnesen, E ;

Rasmussen, K .

NEW ENGLAND JOURNAL OF MEDICINE, 2006, 354 (15) :1578-1588

[3]

Casas JP, 2005, LANCET, V365, P224, DOI 10.1016/S0140-6736(05)70152-5

[4]

CASAS JP, 2007, SPREAD STROKE PREVEN

[5] Homocysteine and risk of ischemic heart disease and stroke -: A meta-analysis [J].

Clarke, R ;

Collins, R ;

Lewington, S ;

Donald, A ;

Alfthan, G ;

Tuomilehto, J ;

Arnesen, E ;

Bonaa, K ;

Blacher, J ;

Boers, GHJ ;

Bostom, A ;

Bots, ML ;

Grobee, DE ;

Brattström, L ;

Breteler, MMB ;

Hofman, A ;

Chambers, JC ;

Kooner, JS ;

Coull, BM ;

Evans, RW ;

Kuller, LH ;

Evers, S ;

Folsom, AR ;

Freyburger, G ;

Parrot, F ;

Genst, J ;

Dalery, K ;

Graham, IM ;

Daly, L ;

Hoogeveen, EK ;

Kostense, PJ ;

Stehouwer, CDA ;

Hopknis, PN ;

Jacques, P ;

Selhub, J ;

Luft, FC ;

Jungers, P ;

Lindgren, A ;

Lolin, YI ;

Loehrer, F ;

Fowler, B ;

Mansoor, MA ;

Malinow, MR ;

Ducimetiere, P ;

Nygard, O ;

Refsum, H ;

Vollset, SE ;

Ueland, PM ;

Omenn, GS ;

Beresford, SAA .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2002, 288 (16) :2015-2022

[6] Endothelin-1 potently induces Leao's cortical spreading depression in vivo in the rat -: A model for an endothelial trigger of migrainous aura? [J].

Dreier, JP ;

Kleeberg, J ;

Petzold, G ;

Priller, J ;

Windmüller, O ;

Orzechowski, HD ;

Lindauer, U ;

Heinemann, U ;

Einhäupl, KM ;

Dirnagl, U .

BRAIN, 2002, 125 :102-112

[7]

Evers S, 1998, EUR J NEUROL, V5, pS51

[8]

Goldstein LB, 2006, STROKE, V37, P1583, DOI 10.1161/01.STR.0000223048.70103.F1

[9] Mechanisms of migraine aura revealed by functional MRI in human visual cortex [J].

Hadjikhani, N ;

del Rio, MS ;

Wu, O ;

Schwartz, D ;

Bakker, D ;

Fischl, B ;

Kwong, KK ;

Cutrer, FM ;

Rosen, BR ;

Tootell, RBH ;

Sorensen, AG ;

Moskowitz, MA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (08) :4687-4692

[10] Is blood homocysteine elevated in migraine? [J].

Hering-Hanit, R ;

Gadoth, N ;

Yavetz, A ;

Gavendo, S ;

Sela, B .

HEADACHE, 2001, 41 (08) :779-781

← 1 2 3 →