Alteration of digital representations in somatosensory cortex in focal hand dystonia

被引:324
作者
Elbert, T [1 ]
Candia, V
Altenmüller, E
Rau, H
Sterr, A
Rockstroh, B
Pantev, C
Taub, E
机构
[1] Univ Konstanz, Dept Psychol, D-78457 Constance, Germany
[2] Hsch Mus & Theater, Inst Mus Physiol & Musiker Med, D-30175 Hannover, Germany
[3] Univ Munster, Inst Expt Audiol, D-48129 Munster, Germany
[4] Univ Alabama, Dept Psychol 415 CH, Birmingham, AL 35294 USA
关键词
cortex; focal dystonia; magnetic source imaging; magnetoencephalography (MEG); plasticity; reorganization; somatotopy;
D O I
10.1097/00001756-199811160-00006
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
FOCAL hand dystonia involves a loss of motor control of one or more digits; it is associated with the repetitive, synchronous movements of the digits made by musicians over periods of many years. Magnetic source imaging revealed that there is a smaller distance (fusion) between the representations of the digits in somatosensory cortex for the affected hand of dystonic musicians than for the hands of non-musician control subjects. The data suggest that use-dependent susceptibility to digital representation fusion in cortex may be involved in the etiology of focal dystonia. A successful therapy for the condition has been developed based on this consideration. NeuroReport 9: 3571-3575 (C) 1998 Lippincott Williams & Wilkins.
引用
收藏
页码:3571 / 3575
页数:5
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