DAVID: Database for annotation, visualization, and integrated discovery

被引：7676

作者：

Dennis, G

Sherman, BT

Hosack, DA

Yang, J

Gao, W

Lane, HC

Lempicki, RA ^{[1
]}

机构：

[1] NCI, Sci Applicat Int Corp, Clin Serv Program, Lab Immunopathogenesis & Bioinformat, Frederick, MD 21702 USA

[2] NIAID, Immunoregulat Lab, NIH, Bethesda, MD 20892 USA

来源：

GENOME BIOLOGY | 2003年 / 4卷 / 09期

关键词：

D O I：

10.1186/gb-2003-4-9-r60

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The distributed nature of biological knowledge poses a major challenge to the interpretation of genome-scale datasets, including those derived from microarray and proteomic studies. This report describes DAVID, a web-accessible program that integrates functional genomic annotations with intuitive graphical summaries. Lists of gene or protein identifiers are rapidly annotated and summarized according to shared categorical data for Gene Ontology, protein domain, and biochemical pathway membership. DAVID assists in the interpretation of genome-scale datasets by facilitating the transition from data collection to biological meaning.

引用

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