White matter changes in dementia: does radiology matter?

被引：10

作者：

Bronge, L. ^{[2
,3
]}

Wahlund, L-O ^{[1
]}

机构：

[1] Karolinska Univ Hosp, NVS Dept, Sect Clin Geriatr, Karolinska Inst, SE-14186 Huddinge, Sweden

[2] Aleris Diagnost Sabbatsberg, SE-11328 Stockholm, Sweden

[3] Karolinska Inst, Div Radiol, Dept Clin Sci Intervent & Technol, SE-14186 Stockholm, Sweden

来源：

BRITISH JOURNAL OF RADIOLOGY | 2007年 / 80卷

关键词：

D O I：

10.1259/bjr/35265137

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

White matter changes are frequently seen on MRI in elderly patients. The significance of these changes is still debated. The origin of white matter changes is heterogeneous but the majority are due to arteriosclerosis in brain vessels. The clinical consequence of the presence of white matter changes in relation to dementia is still unclear. Lately, however, many studies have found a relation between the presence and the degree of white matter changes and cognitive dysfunction. This is most obvious in vascular dementia, but has also been suggested to be of importance in Alzheimer's disease. In this review we discuss the background of these changes and the clinical consequences of them in relation to cognitive disorders.

引用

页码：S115 / S120

页数：6

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