Detection of extended-spectrum β-lactamases in klebsiellae with the oxoid combination disk method

被引：89

作者：

Carter, MW ^{[1
]}

Oakton, KJ ^{[1
]}

Warner, M ^{[1
]}

Livermore, DM ^{[1
]}

机构：

[1] Cent Publ Hlth Lab, Antibiot Resistence Monitoring & Reference Lab, London NW9 5HT, England

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2000年 / 38卷 / 11期

关键词：

D O I：

10.1128/JCM.38.11.4228-4232.2000

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The Oxoid combination disk method for detecting extended-spectrum beta -lactamases (ESBLs) depends on comparing the inhibition zones of cefpodoxime (10-mug) and cefpodoxime-plus-clavulanate (10- plus 1-mug) disks. The presence of clavulanate enlarged the zones for all of 180 ESBL-producing klebsiellae by greater than or equal to5 mm, whereas zones for cefpodoxime-susceptible isolates and cefpodoxime-resistant isolates with AmpC and K1 beta -lactamases were enlarged by less than or equal to1 mm. Good discrimination was achieved with either the NCCLS or the British disk method.

引用

页码：4228 / 4232

页数：5

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