Nonconvulsive status epilepticus with frontal features: quantitating severity of subclinical epileptiform discharges provides a marker for treatment efficacy, recurrence and outcome

被引：8

作者：

Licht, EA

Fujikawa, DG

机构：

[1] VA Greater Los Angeles Healthcare Syst, Dept Neurol, Sepulveda Ambulatory Care Ctr, Sepulveda, CA 91343 USA

[2] Nursing Home Care Unit, Sepulveda, CA 91343 USA

[3] Univ Calif Los Angeles, Sch Med, Dept Neurol, Los Angeles, CA 90024 USA

[4] Univ Calif Los Angeles, Sch Med, Inst Brain Res, Los Angeles, CA 90024 USA

来源：

EPILEPSY RESEARCH | 2002年 / 51卷 / 1-2期

关键词：

nonconvulsive status epilepticus; subclinical epileptiform discharges; subclinical seizures; frontal lobe seizures; cognitive deficits;

D O I：

10.1016/S0920-1211(02)00107-9

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Nonconvulsive status epilepticus (NCSE) is difficult to diagnose but is an important cause of cognitive impairment. Electroencephalogram (EEG) monitoring is required for diagnosis and treatment. Little is known regarding the stability of subclinical epileptiform discharges (SEDs) preceding NCSE nor what strategies may optimize patient outcomes. We report extended follow-up of patients with recurrent frontal SEDs, integrating EEG and cognitive findings before and following treatment of NCSE, and show that quantitating SED severity provides an objective marker of treatment efficacy and recurrence. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：13 / 21

页数：9

共 17 条

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