Role of Lipoprotein-Associated Phospholipase A2 in Atherosclerosis

被引：21

作者：

Lavi, Shahar ^{[1
]}

Herrmann, Joerg ^{[1
]}

Lavi, Ronit ^{[1
]}

McConnell, Joseph P. ^{[1
]}

Lerman, Lilach O. ^{[1
]}

Lerman, Amir ^{[1
]}

机构：

[1] Mayo Clin, Div Cardiovasc Dis, Rochester, MN 55905 USA

来源：

CURRENT ATHEROSCLEROSIS REPORTS | 2008年 / 10卷 / 03期

关键词：

D O I：

10.1007/s11883-008-0036-9

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) is a biomarker that can be used to assess the risk for cardiovascular disease and events. In addition to being a useful marker of a risk factor, several studies suggest that Lp-PLA(2) has a pathophysiologic role in the atherosclerotic disease process. In this article, we review this aspect and its therapeutic implications.

引用

页码：230 / 235

页数：6

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