New insights into the role of CXCR4 in prostate cancer metastasis

被引：34

作者：

Gladson, Candece L. ^{[1
]}

Welch, Danny R. ^{[2
]}

机构：

[1] Univ Alabama, Dept Pathol, Div Neuropathol, Birmingham, AL 35294 USA

[2] Univ Alabama, Dept Pathol, Div Mol & Cellular Pathol, Birmingham, AL 35294 USA

来源：

CANCER BIOLOGY & THERAPY | 2008年 / 7卷 / 11期

关键词：

CXCR4; prostate cancer; metastasis; SDF1; alpha; CXCL12; adhesion; signaling;

D O I：

10.4161/cbt.7.11.7218

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：1849 / 1851

页数：3

共 18 条

[1] Chemokine receptor CXCR4 expression and prognosis in patients with metastatic prostate cancer [J].

Akashi, Takuya ;

Koizumi, Keiichi ;

Tsuneyama, Koichi ;

Saiki, Ikuo ;

Takano, Yasuo ;

Fuse, Hideki .

CANCER SCIENCE, 2008, 99 (03) :539-542

[2] CXCL12/CXCR4 signaling activates Akt-1 and MMP-9 expression in prostate cancer cells: The role of bone microenvironment-associated CXCL12 [J].

Chinni, SR ;

Sivalogan, S ;

Dong, Z ;

Trindade, JC ;

Deng, XY ;

Bonfil, RD ;

Cher, ML .

PROSTATE, 2006, 66 (01) :32-48

[3] CXCR4 chemokine receptor mediates prostate tumor cell adhesion through α5 and β3 Integrins [J].

Engl, Tobias ;

Relja, Borna ;

Marian, Dana ;

Blumenberg, Christa ;

Mueller, Iris ;

Beecken, Wolf-Dietrich ;

Jones, Jon ;

Ringel, Eva M. ;

Bereiter-Hahn, Juergen ;

Jonas, Dietger ;

Blaheta, Roman A. .

NEOPLASIA, 2006, 8 (04) :290-301

[4] Transduction - Integrin signaling [J].

Giancotti, FG ;

Ruoslahti, E .

SCIENCE, 1999, 285 (5430) :1028-1032

[5]

Humperey P, 2006, SILVERBERGS PRINCIPL, P1791

[6] Up-regulation of CXCR4 expression in PC-3 cells by stromal-derived factor-1α (CXCL12) increases endothelial adhesion and transendothelial migration:: Role of MEK-ERK signaling pathway-dependent NF-κB activation [J].

Kukreja, P ;

Abdel-Mageed, AB ;

Mondal, D ;

Liu, K ;

Agrawal, KC .

CANCER RESEARCH, 2005, 65 (21) :9891-9898

[7] CXCR4, inhibitors and mechanisms of action [J].

Liang, Xiangyang .

CHEMICAL BIOLOGY & DRUG DESIGN, 2008, 72 (02) :97-110

[8] Osteoblast-conditioned media influence the expression of E-selectin on bone-derived vascular endothelial cells [J].

Makuch, Lauren A. ;

Sosnoski, Donna M. ;

Gay, Carol V. .

JOURNAL OF CELLULAR BIOCHEMISTRY, 2006, 98 (05) :1221-1229

[9] Metastasis to bone: Causes, consequences and therapeutic opportunities [J].

Mundy, GR .

NATURE REVIEWS CANCER, 2002, 2 (08) :584-593

[10] The chemokine receptor CXCR4 - A homing device for hypoxic cancer cells? [J].

Pore, Nabendu ;

Maity, Amit .

CANCER BIOLOGY & THERAPY, 2006, 5 (11) :1563-1565

← 1 2 →