Arginine vasopressin in the management of vasodilatory hypotension after cardiac transplantation

被引：56

作者：

Argenziano, M ^{[1
]}

Chen, JM ^{[1
]}

Cullinane, S ^{[1
]}

Choudhri, AF ^{[1
]}

Rose, EA ^{[1
]}

Smith, CR ^{[1
]}

Edwards, NM ^{[1
]}

Landry, DW ^{[1
]}

Oz, MC ^{[1
]}

机构：

[1] Columbia Univ Coll Phys & Surg, Dept Surg, New York, NY 10032 USA

来源：

JOURNAL OF HEART AND LUNG TRANSPLANTATION | 1999年 / 18卷 / 08期

关键词：

D O I：

10.1016/S1053-2498(99)00038-8

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Vasodilatory hypotension requiring the administration of catecholamine pressors may occur following cardiopulmonary bypass. We investigated the hemodynamic response to arginine vasopressin (AVP) in 20 patients who developed vasodilatory hypotension after cardiac transplantation. In this cohort, AVP infusion (0.1 U/min) significantly increased mean arterial pressure and decreased norepinephrine requirements, allowing rapid discontinuation of norepinephrine infusions in 7 patients. Judicious use of this novel agent in appropriately selected patients may minimize end-organ sequelae of hypotension and high-dose catecholamine therapy.

引用

页码：814 / 817

页数：4

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