QT interval prolongation associated with venlafaxine administration

被引：39

作者：

Letsas, K

Korantzopoulos, P ^{[1
]}

Pappas, L

Evangelou, D

Efremidis, M

Kardaras, F

机构：

[1] G Hatzikosta Gen Hosp, Dept Cardiol, Ioannina 45001, Greece

[2] Evangelismos Gen Hosp Athens, Dept Cardiol 2, Athens 10676, Greece

来源：

INTERNATIONAL JOURNAL OF CARDIOLOGY | 2006年 / 109卷 / 01期

关键词：

venlafaxine; long QT; side effects; antidepressant drug;

D O I：

10.1016/j.ijcard.2005.03.065

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A significant number of non-antiarrhythmic drugs including psychotropic agents have been shown to prolong cardiac repolarization increasing the risk for torsade de pointes ventricular tachycardia. We briefly describe a 60-year-old woman who admitted to the hospital due to hypertension and mild dyspnea having a prolonged QT interval (QTc: 582 ms). The patient had a known history of depression treated with venlafaxine. The QT interval normalised a few days after cessation of the antidepressant agent. This is the first report of venlafaxine-induced QT interval prolongation. (c) 2005 Elsevier Ireland Ltd. All rights reserved.

引用

页码：116 / 117

页数：2

共 10 条

[1] Conduction disturbances associated with venlafaxine [J].