Major advances in the treatment of stroke

被引:19
作者
Blanco, Miguel [1 ]
Castillo, Jose [1 ]
机构
[1] Hosp Clin Univ, Dept Neurol, Clin Neurosci Res Lab, Inst Sanitary Res Santiago de Compostela IDIS,Neu, Santiago De Compostela 15706, Spain
关键词
ACUTE ISCHEMIC-STROKE; ATRIAL-FIBRILLATION; CRYPTOGENIC STROKE; CITICOLINE; RISK;
D O I
10.1038/nrneurol.2012.274
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Several clinical trials and experimental studies that could have a major impact on the treatment of patients with ischaemic stroke were published in 2012. The studies cover all therapeutic options, including stroke prevention, recanalization and thrombolysis, neuroprotection, and promising new therapeutic approaches focused on neurorepair. Blanco, M. & Castillo, J. Nat. Rev. Neurol. 9, 68-70 (2013); published online 8 January 2013; doi:10.1038/nrneurol.2012.274
引用
收藏
页码:68 / 70
页数:3
相关论文
共 9 条
[1]   Oral citicoline in acute ischemic stroke -: An individual patient data pooling analysis of clinical trials [J].
Dávalos, A ;
Castillo, J ;
Alvarez-Sabín, J ;
Secades, JJ ;
Mercadal, J ;
López, S ;
Cobo, E ;
Warach, S ;
Sherman, D ;
Clark, WM ;
Lozano, R .
STROKE, 2002, 33 (12) :2850-2857
[2]   Citicoline in the treatment of acute ischaemic stroke: an international, randomised, multicentre, placebo-controlled study (ICTUS trial) [J].
Davalos, Antoni ;
Alvarez-Sabin, Jose ;
Castillo, Jose ;
Diez-Tejedor, Exuperio ;
Ferro, Jose ;
Martinez-Vila, Eduardo ;
Serena, Joaquin ;
Segura, Tomas ;
Cruz, Vitor T. ;
Masjuan, Jaime ;
Cobo, Erik ;
Secades, Julio J. .
LANCET, 2012, 380 (9839) :349-357
[3]   Closure or Medical Therapy for Cryptogenic Stroke with Patent Foramen Ovale [J].
Furlan, Anthony J. ;
Reisman, Mark ;
Massaro, Joseph ;
Mauri, Laura ;
Adams, Harold ;
Albers, Gregory W. ;
Felberg, Robert ;
Herrmann, Howard ;
Kar, Saibal ;
Landzberg, Michael ;
Raizner, Albert ;
Wechsler, Lawrence .
NEW ENGLAND JOURNAL OF MEDICINE, 2012, 366 (11) :991-999
[4]   Subclinical Atrial Fibrillation and the Risk of Stroke [J].
Healey, Jeff S. ;
Connolly, Stuart J. ;
Gold, Michael R. ;
Israel, Carsten W. ;
Van Gelder, Isabelle C. ;
Capucci, Alessandro ;
Lau, C. P. ;
Fain, Eric ;
Yang, Sean ;
Bailleul, Christophe ;
Morillo, Carlos A. ;
Carlson, Mark ;
Themeles, Ellison ;
Kaufman, Elizabeth S. ;
Hohnloser, Stefan H. .
NEW ENGLAND JOURNAL OF MEDICINE, 2012, 366 (02) :120-129
[5]   Clinical and imaging findings in cryptogenic stroke patients with and without patent foramen ovale - The PFO-ASA study [J].
Lamy, C ;
Giannesini, C ;
Zuber, M ;
Arquizan, C ;
Meder, JF ;
Trystram, D ;
Coste, J ;
Mas, JL .
STROKE, 2002, 33 (03) :706-711
[6]   Human-Induced Pluripotent Stem Cells form Functional Neurons and Improve Recovery After Grafting in Stroke-Damaged Brain [J].
Oki, Koichi ;
Tatarishvili, Jemal ;
Wood, James ;
Koch, Philipp ;
Wattananit, Somsak ;
Mine, Yutaka ;
Monni, Emanuela ;
Tornero, Daniel ;
Ahlenius, Henrik ;
Ladewig, Julia ;
Bruestle, Oliver ;
Lindvall, Olle ;
Kokaia, Zaal .
STEM CELLS, 2012, 30 (06) :1120-1133
[7]   The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3]): a randomised controlled trial [J].
Sandercock, Peter ;
Wardlaw, Joanna M. ;
Lindley, Richard I. ;
Dennis, Martin ;
Cohen, Geoff ;
Murray, Gordon ;
Innes, Karen ;
Venables, Graham ;
Czlonkowska, Anna ;
Kobayashi, Adam ;
Ricci, Stefano ;
Murray, Veronica ;
Berge, Eivind ;
Slot, Karsten Bruins ;
Hankey, Graeme J. ;
Correia, Manuel ;
Peeters, Andre ;
Matz, Karl ;
Lyrer, Phillippe ;
Gubitz, Gord ;
Phillips, Stephen J. ;
Arauz, Antonio ;
Baigent, Colin ;
Chadwick, David ;
Tyrrell, Pippa ;
Lowe, Gordon ;
Farrall, Andrew ;
von Kummer, Rudiger ;
Cala, Lesley ;
von Heijne, Anders ;
Morris, Zoe ;
Adami, Alessandro ;
Potter, Gillian ;
Brady, Nick ;
Collins, Rory ;
Bath, Philip ;
van Gijn, Jan ;
Gray, Richard ;
Hart, Robert ;
Yusuf, Salim ;
Muir, Keith ;
Brainin, Michael ;
Engelter, Stefan ;
Terent, Andreas ;
Norrving, Bo ;
Wester, Per ;
Clark, Alison ;
Perry, David ;
Soosay, Vera ;
Buchanan, David .
LANCET, 2012, 379 (9834) :2352-2363
[8]   Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors [J].
Takahashi, Kazutoshi ;
Yamanaka, Shinya .
CELL, 2006, 126 (04) :663-676
[9]   ATRIAL-FIBRILLATION AS AN INDEPENDENT RISK FACTOR FOR STROKE - THE FRAMINGHAM-STUDY [J].
WOLF, PA ;
ABBOTT, RD ;
KANNEL, WB .
STROKE, 1991, 22 (08) :983-988