In silico patent searching reveals a new cannabinoid receptor

被引：248

作者：

Baker, D

Pryce, G

Davies, WL

Hiley, CR

机构：

[1] UCL, Inst Neurol, Dept Neuroinflammat, London WC1N 1PJ, England

[2] Univ Cambridge, Dept Pharmacol, Cambridge CB2 1PD, England

来源：

TRENDS IN PHARMACOLOGICAL SCIENCES | 2006年 / 27卷 / 01期

关键词：

D O I：

10.1016/j.tips.2005.11.003

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Increasing evidence suggests that some cannabinoids mediate their effects independently of the known cannabinoid CB1 and CB2 receptors. Two recently published patents indicate that several cannabinoid receptor ligands also bind to the orphan G-protein-coupled receptor GPR55. This receptor is reported to be expressed in several tissues and might function in lipid or vascular biology. Thus, GPR55 might represent a new cannabinoid receptor.

引用

页码：1 / 4

页数：4

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