The SWISS-PROT protein sequence data bank and its supplement TrEMBL

被引:372
作者
Bairoch, A [1 ]
Apweller, R [1 ]
机构
[1] EUROPEAN BIOINFORMAT INST,EMBL OUTSTN,HINXTON CB10 1SD,CAMBS,ENGLAND
关键词
D O I
10.1093/nar/25.1.31
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
SWISS-PROT is a curated protein sequence database which strives to provide a high level of annotations (such as the description of the function of a protein, structure of its domains, post-translational modifications, variants, etc.), a minimal level of redundancy and high level of integration with other databases, Recent developments of the database include: an increase in the number and scope of model organisms; cross-references to two additional databases; a variety of new documentation files and the creation of TrEMBL, a computer annotated supplement to SWISS-PROT. This supplement consists of entries in SWISS-PROT-like format derived from the translation of all coding sequences (CDS) in the EMBL nucleotide sequence database, except the CDS already included in SWISS-PROT.
引用
收藏
页码:31 / 36
页数:6
相关论文
共 8 条
[1]   A NEW-GENERATION OF INFORMATION-RETRIEVAL TOOLS FOR BIOLOGISTS - THE EXAMPLE OF THE EXPASY WWW SERVER [J].
APPEL, RD ;
BAIROCH, A ;
HOCHSTRASSER, DF .
TRENDS IN BIOCHEMICAL SCIENCES, 1994, 19 (06) :258-260
[2]   The SWISS-PROT protein sequence data bank and its new supplement TREMBL [J].
Bairoch, A ;
Apweiler, R .
NUCLEIC ACIDS RESEARCH, 1996, 24 (01) :21-25
[3]   The PROSITE database, its status in 1995 [J].
Bairoch, A ;
Bucher, P ;
Hofmann, K .
NUCLEIC ACIDS RESEARCH, 1996, 24 (01) :189-196
[4]   The ENZYME data bank in 1995 [J].
Bairoch, A .
NUCLEIC ACIDS RESEARCH, 1996, 24 (01) :221-222
[5]  
BAIROCH A, 1996, SWISS PROT PROTEIN S
[6]   THE HUMAN MYOCARDIAL 2-DIMENSIONAL GEL PROTEIN DATABASE - UPDATE-1994 [J].
CORBETT, JM ;
WHEELER, CH ;
BAKER, CS ;
YACOUB, MH ;
DUNN, MJ .
ELECTROPHORESIS, 1994, 15 (11) :1459-1465
[7]  
*FLYB CONS, 1996, NUCLEIC ACIDS RES, V24, P53
[8]   The European Bioinformatics Institute (EBI) databases [J].
RodriguezTome, P ;
Stoehr, PJ ;
Cameron, GN ;
Flores, TP .
NUCLEIC ACIDS RESEARCH, 1996, 24 (01) :6-12