Cancer biomarkers - An invitation to the table

被引：159

作者：

Dalton, William S.

Friend, Stephen H. ^{[1
]}

机构：

[1] Univ S Florida, H Lee Moffitt Canc Ctr, Tampa, FL 33613 USA

[2] Merck Res Labs, West Point, PA 19486 USA

来源：

SCIENCE | 2006年 / 312卷 / 5777期

关键词：

D O I：

10.1126/science.1125948

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The allure of the emerging genomic technologies in cancer is their ability to generate new biomarkers that predict how individual cancer patients will respond to various treatments. However, productive implementation of cancer biomarkers into patient care will require fundamental changes in how we consider approvals for cancer indications and how we track patient responses. Here we briefly describe ongoing efforts to identify and to validate cancer biomarkers, discuss the technological hurdles that lie ahead, and then focus on the more pressing political and cultural issues that, if left unheeded, could derail many of the anticipated benefits of biomarker research.

引用

页码：1165 / 1168

页数：4

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