Phagocytosis and innate immunity

被引：427

作者：

Greenberg, S

Grinstein, S

机构：

[1] Columbia Univ, Dept Med, New York, NY 10032 USA

[2] Columbia Univ, Dept Pharmacol, New York, NY 10032 USA

[3] Hosp Sick Children, Res Inst, Programme Cell Biol, Toronto, ON M5G 1X8, Canada

来源：

CURRENT OPINION IN IMMUNOLOGY | 2002年 / 14卷 / 01期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0952-7915(01)00309-0

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Phagocytosis is an evolutionarily conserved process utilized by many cells to ingest microbial pathogens, and apoptotic and necrotic corpses. Recent investigation has revealed a fundamental requirement for two co-ordinated cellular processes - cytoskeletal alterations and membrane trafficking - in the phagocytic event. Some elements of this machinery are co-opted by certain pathogens to gain entry into host cells.

引用

收藏

页码：136 / 145

页数：10

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