The TRP channels, a remarkably functional family

被引:691
作者
Montell, C [1 ]
Birnbaumer, L
Flockerzi, V
机构
[1] Johns Hopkins Univ, Sch Med, Dept Biol Chem, Baltimore, MD 21205 USA
[2] Johns Hopkins Univ, Sch Med, Dept Neurosci, Baltimore, MD 21205 USA
[3] NIEHS, Res Triangle Pk, NC 27709 USA
[4] Univ Saarland, Inst Pharmakol & Toxikol, D-66421 Homburg, Germany
关键词
D O I
10.1016/S0092-8674(02)00670-0
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
TRIP cation channels display an extraordinary assortment of selectivities and activation mechanisms, some of which represent previously unrecognized modes for regulating ion channels. Moreover, the biological roles of TRP channels appear to be equally diverse and range from roles in pain perception to male aggression.
引用
收藏
页码:595 / 598
页数:4
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