The role of dendritic cells in the induction and regulation of immunity to microbial infection

被引：223

作者：

Sousa, CRE

Sher, A

Kaye, P

机构：

[1] Imperial Canc Res Fund, Immunobiol Lab, London WC2A 3PX, England

[2] NIAID, Immunobiol Sect, Parasit Dis Lab, NIH, Bethesda, MD 20892 USA

[3] Univ London London Sch Hyg & Trop Med, Immunol Unit, London WC1E 7HT, England

来源：

CURRENT OPINION IN IMMUNOLOGY | 1999年 / 11卷 / 04期

关键词：

D O I：

10.1016/S0952-7915(99)80066-1

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Dendritic cells (DCs) play a critical role in the initiation and regulation of immune responses. Recent advances have begun to uncover the nature and diversity of DC-pathogen interactions and the modulation of DC function by microbial stimuli. Antigen pulsed DCs have also been shown in several infection models to induce high levels of protective immunity and to display immunotherapeutic potential. The study of the function of DCs in the response to infection is thus an exciting and rapidly expanding field with important implications for both fundamental and clinical immunology.

引用

页码：392 / 399

页数：8

共 85 条

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