Diffusion-weighted imaging with navigated interleaved echo-planar imaging and a conventional gradient system

被引:84
作者
Bammer, P
Stollberger, R
Augustin, M
Simbrunner, J
Offenbacher, H
Kooijman, H
Ropele, S
Kapeller, P
Wach, P
Ebner, F
Fazekas, F
机构
[1] Graz Univ, Magnet Resonance Inst, A-8036 Graz, Austria
[2] Graz Univ, Dept Neurol, A-8036 Graz, Austria
[3] Graz Univ, Dept Radiol, A-8036 Graz, Austria
[4] Philips Med Syst, Hamburg, Germany
[5] Graz Univ Technol, Inst Elect & Biomed Engn, A-8010 Graz, Austria
关键词
brain; infarction; MR; magnetic resonance (MR); diffusion study; echo planar; tissue characterization;
D O I
10.1148/radiology.211.3.r99jn15799
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
PURPOSE: To demonstrate the technical feasibility; and precision of a navigated diffusion-weighted(DW) MR imaging method with interleaved echo-planar imaging and test its diagnostic sensitivity for detection of ischemic stroke. MATERIALS AND METHODS: Apparent diffusion coefficient (ADC) measurements were performed in phantoms, and six healthy adult volunteers were examined to determine intrasubject (precision) and intersubject (reference range) variations in absolute ADC and relative ADC (rADC) measurements,imaging maps and lesion rADC values were:also;obtained in 34 consecutive stroke patients to evaluate the sensitivity and reliability of DW-interleaved echo-planar:imaging for detection of ischemic brain damage. RESULTS: Phantom and volunteer ADC values were in excellent agreement with published data. The intra;subject variation of rADC was 6.2% . The ADC precision ranged from 6.5% in the subcortical white matter in the frontal lobe to 12.9% in the head of the caudate nucleus. Interleaved echo-planar imaging enabled rapid acquisition of high-quality images of the entire brain without substantial artifacts. Within the ist week, the sensitivity of DW-interleaved echo-planar imaging for detection of acute infarction was 90% (18:of 20 true-positive studies); and : independent of lesion location. CONCLUSION: aw-ininterleaved echo-planar with phase navigation and cardiac triggering i;robust reliable; and fast. With high sensitivity for detection of early ischemic infarction, it is useful for examining stroke:patients:by using MR systems with conventional gradient hardware.
引用
收藏
页码:799 / 806
页数:8
相关论文
共 38 条
[1]   ANALYSIS AND CORRECTION OF MOTION ARTIFACTS IN-DIFFUSION WEIGHTED IMAGING [J].
ANDERSON, AW ;
GORE, JC .
MAGNETIC RESONANCE IN MEDICINE, 1994, 32 (03) :379-387
[2]  
Bammer R, 1997, INT CONGR SER, V1134, P111
[3]   Diffusion-weighted interleaved echo-planar imaging with a pair of orthogonal navigator echoes [J].
Butts, K ;
deCrespigny, A ;
Pauly, JM ;
Moseley, M .
MAGNETIC RESONANCE IN MEDICINE, 1996, 35 (05) :763-770
[4]   Isotropic diffusion-weighted and spiral-navigated interleaved EPI for routine imaging of acute stroke [J].
Butts, K ;
Pauly, J ;
deCrespigny, A ;
Moseley, M .
MAGNETIC RESONANCE IN MEDICINE, 1997, 38 (05) :741-749
[5]  
CHIEN D, 1992, AM J NEURORADIOL, V13, P1097
[6]   Diffusion MRI: Precision, accuracy and flow effects [J].
Conturo, TE ;
McKinstry, RC ;
Aronovitz, JA ;
Neil, JJ .
NMR IN BIOMEDICINE, 1995, 8 (7-8) :307-332
[7]   NAVIGATED DIFFUSION IMAGING OF NORMAL AND ISCHEMIC HUMAN BRAIN [J].
DECRESPIGNY, AJ ;
MARKS, MP ;
ENZMANN, DR ;
MOSELEY, ME .
MAGNETIC RESONANCE IN MEDICINE, 1995, 33 (05) :720-728
[8]   ADAPTIVE TECHNIQUE FOR HIGH-DEFINITION MR IMAGING OF MOVING STRUCTURES [J].
EHMAN, RL ;
FELMLEE, JP .
RADIOLOGY, 1989, 173 (01) :255-263
[9]   PHASE ERRORS IN MULTISHOT ECHO-PLANAR IMAGING [J].
FEINBERG, DA ;
OSHIO, K .
MAGNETIC RESONANCE IN MEDICINE, 1994, 32 (04) :535-539
[10]   USE OF A PROJECTION RECONSTRUCTION METHOD TO DECREASE MOTION SENSITIVITY IN DIFFUSION-WEIGHTED MRI [J].
GMITRO, AF ;
ALEXANDER, AL .
MAGNETIC RESONANCE IN MEDICINE, 1993, 29 (06) :835-838