Contribution of stent underexpansion to recurrence after sirolimus-eluting stent implantation for in-stent restenosis

被引：245

作者：

Fujii, K ^{[1
]}

Mintz, GS ^{[1
]}

Kobayashi, Y ^{[1
]}

Carlier, SG ^{[1
]}

Takebayashi, H ^{[1
]}

Yasuda, T ^{[1
]}

Moussa, I ^{[1
]}

Dangas, G ^{[1
]}

Mehran, R ^{[1
]}

Lansky, AJ ^{[1
]}

Reyes, A ^{[1
]}

Kreps, E ^{[1
]}

Collins, M ^{[1
]}

Colombo, A ^{[1
]}

Stone, GW ^{[1
]}

Teirstein, PS ^{[1
]}

Leon, MB ^{[1
]}

Moses, JW ^{[1
]}

机构：

[1] Lenox Hill Heart & Vasc Inst, Cardiovasc Res Fdn, New York, NY 10021 USA

来源：

CIRCULATION | 2004年 / 109卷 / 09期

关键词：

ultrasonics; restenosis; stents;

D O I：

10.1161/01.CIR.0000121327.67756.19

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background - We used intravascular ultrasound (IVUS) to evaluate recurrence after sirolimus-eluting stent (SES) implantation treatment of in-stent restenosis (ISR). Methods and Results - Forty-eight ISR lesions ( 41 patients with objective evidence of ischemia) were treated with SES. Recurrent ISR was identified in 11 lesions ( all focal); repeat revascularization was performed in 10. These were compared with 16 patients ( 19 lesions) without recurrence as documented by angiography. Nine of 11 recurrent lesions had a minimum stent area (MSA) < 5.0 mm(2) versus 5 of 19 nonrecurrent lesions ( P = 0.003); 7 of 11 recurrent lesions had an MSA < 4.0 mm(2) versus 4 of 19 nonrecurrent lesions (P = 0.02); and 4 of 11 recurrent lesions had an MSA < 3.0 mm(2) versus 1 of 19 nonrecurrent lesions ( P = 0.03). A gap between SESs was identified in 3 of 11 recurrences versus 1 of 19 nonrecurrent lesions. Conclusions - Stent underexpansion is a significant cause of failure after SES implantation treatment of ISR.

引用

页码：1085 / 1088

页数：4

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