Introduction: P2 receptors

被引：209

作者：

Burnstock, G ^{[1
]}

机构：

[1] UCL Royal Free & Univ Coll, Autonom Neurosci Inst, London NW3 2PF, England

来源：

CURRENT TOPICS IN MEDICINAL CHEMISTRY | 2004年 / 4卷 / 08期

关键词：

D O I：

10.2174/1568026043451014

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The current status of ligand gated ion channel P2X and G protein-coupled P2Y receptor subtypes is described. This is followed by a summary of what is known of the distribution and roles of these receptor subtypes. Potential therapeutic targets of purinoceptors are considered, including those involved in cardiovascular, nervous, respiratory, urinogenital, Gastrointestinal, musculo-skeletal and special sensory diseases, as well as inflammation, cancer and diabetes. Lastly, there are some speculations about future developments in the purinergic signalling field.

引用

页码：793 / 803

页数：11

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